Evaluation Report Publications of the Academy of Finland 1/11

Research profile
The unit is evenly devoted to basic and applied research and works in the border area 
between chemistry and biology: “the problems of biology investigated with the tools 
and concepts of chemistry”. The chemical biology/biological chemistry research at 
the unit is focused on two main themes: (i) Synthetic biomolecular chemistry and 
analytical chemistry, with synthesis of various bioactive molecules, phosphonates, 

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peptides, polyamines for anti-cancer drug development, imaging, and radiochemistry 
as core topics, and (ii) Computerised NMR and NMR metabolomics, with a long 
tradition of working with analysis and predictions of NMR spectra of biomolecules 
using libraries and models taking into account (intra-/inter-) molecular motion. The 
activities in metabolomics are part of the national group for computational medicine 
and mainly focused on NMR spectroscopy of new potential drug molecules.