ABBREVIATIONS
CCD – Charge Coupled Device
CT – Computed
Tomography
IMRT – Intensity Modulated Radiation Therapy
LET – Linear Energy
Transfer
MOSFET – Metal Oxide Semiconductor Field Effect Transistor
MU – Monitor Unit
OSLD – Optically Stimulated Luminescent Dosimeter
PMT – Photomultiplier Tube
PSD – Plastic
Scintillation Detector
ROI – Region of Interest
SNR – Signal
to Noise Ratio
SOBP – Spread Out Bragg Peak
TLD – Thermoluminescent Dosimeter
TPS – Treatment Planning
System
xiv
1.1 Purpose Statement
The primary objective of this research is to implement plastic scintillation detectors for
in
vivo dosimetry and to evaluate the practicality of doing so.
In vivo dosimetry - direct
measurement of dose delivered to patients during treatment – is a valuable tool for
treating patients safely and effectively. However, its routine practice is uncommon
despite evidence that it can identify treatment errors that would otherwise go undetected
(Fiorino
et al. 2000). This is due in part to the labor intensive nature of
in vivo dosimetry
and a lack of ideally suited detectors (Edwards 2007, Williams and McKenzie 2008). By
demonstrating the plastic scintillation detectors are easy to use, highly accurate
in vivo
detectors, it is hoped that this research will contribute
to increased adoption of in vivo
dosimetry and enhance patient safety.
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