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oevren die, whereas n1ost young people and children have only mild diseases (non-pneumonia or mild pneun1onia) or are asyn1ptomatic⁹'⁸¹'g . Notably, the risk of disease was not higher for pregnant women. However, evidence of transplacental transn1ission of SARS-CoV-2 from an infected mother to a neonate was reported, although it was an isolated case ³· \ On infection, the most con1mon syn1ptoms are fever, fatigue and dry cough¹³,ou. ⁰, ¹• Less comn1on symptoms include sputum production, headache, haemoptysis, diarrhoea, anorexia, sore throat, chest pain, chills and nausea and vomiting in studies of patients in China.'no. o)H. Self-reported olfac- tory and taste disorders were also reported by patients in Italy ;. Most people showed signs of diseases after an incubation period of 1-14 days (most con1n1only around 5 days), and dyspnoea and pneun1onia developed within a median time of 8 days from illness onset⁹•
In a report of 72,314 cases in China, 81% of the
cases were classified as mild, 14% were severe cases that required ventilation in an intensive care unit (ICU) and a 5% were critical (that is, the patients had respiratory failure, septic shock and/or multiple organ dysfunction or failurerJ·⁸⁶. On adn1ission, ground-glass opacity was the most common radiologic finding on chest con1puted tomography (CT) ¹³'⁶⁰· ⁰·⁸¹. Most patients also developed marked lyn1phopenia, similar to what was observed in patients with SARS and MERS, and non-survivors devel­ oped severer lyn1phopenia over tin1e1J.(io,⁸⁰·⁸¹• Con1pared
with non-ICU patients, ICU patients had higher levels
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was linked to a family member and 26 children had history of travel/residence to Hubei province in China. All the patients were either asymptomatic (9%) or had mild disease. No severe or critical cases were seen. The most common symptoms were fever (50%) and cough (38%). All patients recovered with symptomatic therapy and there were no deaths. One case of severe pneumonia and multiorgan dysfunction in a child has also been reported [19]. Similarly the neonatal cases that have been reported have been mild [20].