Samarqand davlat tibbiyot universiteti farmakalogiya kafedrasi farmakalogiya fanidan

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Organizimda pirazinamidaza orqali faollashtiriladigan dori vosita

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Sil kasalikni davolashda samaradorligi kam vosita

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4-Topshiriq. Farmakodinamikadan keltirilgan savollarga rejalashtirilgan javoblardan to‘g‘risini tanlash.
1. I-qatorli silga qarshi moddalar: a) streptomitsin; b) rifampitsin; v) natriya paraaminosalitsilat; g) izoniazid; d) etambutol; e) sikloserin.
2. II-qatorli silga qarshi moddalar: a) streptomitsin; b) rifampitsin; v) natriya paraaminosalitsilat; g) izoniazid; d) etambutol; e) sikloserin.
3. Streptomitsinni antibakterial ta’sirini spektri: a) diplokokklar; b) streptokokklar va stafilakokklar; v) vabo tayoqchasi; g) sil mikobakteriyasi; d) spiroxetalar va leptosperalar.
4. Streptomitsinn qo‘llanilganda kelib chiqadigan nojo‘ya ta’sirlar: a) allaergik reaksiyalar; b) eshitishni pasayishi va vestibulyar buzilishlar; v) gemoliz; g) dizbakterioz; d) buyrak funksiyasi buzilishi.
5. Natriy paraaminosalitsilatni tuberkulostatik ta’sir mexanizmi: a) xujayra qobig‘ini hosil bo‘lishini buzilishi; b) mikobakteriyalarni oqsil hosil bo‘lishini falajlanishi; v) mikobakteriyalarni folat kislota hosil bo‘lish jarayonida paraaminobenzoy kislotani konkurent antagonizmi.