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1
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Specify the drug with antiandrogenic activity:
a) tamoxifen
b) aminoglutimide
c) flutamide
d) testosterone
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6
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For what type of mycoses is alcohol iodine solution used:
a) with systemic mycoses
b) with epiermomycosis
c) with candidiasis
d) for all types of mycoses
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2
|
With the combined appointment of anticancer drugs, the following effect is used:
a) increased antitumor activity as a result of the use of drugs with different mechanisms of action
b) increased antitumor activity as a result of the use of drugs with the same mechanisms of action
c) enhancing the immunostimulatory effect
d) increased mitotic activity of cells
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7
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Note the preparation of phosphorus from the brain of slaughtered cattle in case of overwork.
a) phosphodene
b) calcium glycerophosphate
c) cyclophosphamide
d) cerebrolecithin
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3
|
Specify a drug that does not belong to nucleoside analogues:
a) acyclovir
b) zidovudine
c) saquinavir
d) idoxuridine
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8
|
Show persistent type of teturami.
a) esperal
b) phenazepam
c) suprastin
d) trimetine
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4
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Specify the mechanism of action of ethylene tetrachloride:
a) destruction of integumentary tissues of helminths
b) inhibits metabolic processes in the cell (cell poison)
c) inhibition of the energy processes of helminths
d) dysfunction of neuromuscular transmission in helminths
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9
|
The effects of NSAIDs may be mediated by:
a) inhibition of prostaglandin synthesis by inhibition of phospholipase a2
b) inhibition of prostaglandin synthesis by inhibition of cyclooxygenase
c) inhibition of leukotriene synthesis by inhibition of 5-lipoxygenase
d) inhibition of the release of bradykinin, histamine, serotonin from blood cells
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5
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Specify a pyrimidine derivative with antimalarial properties:
a) primaquine
b) chloridine
c) hingamin
d) mefloquine
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10
|
Mark the main indication for the use of testosterone preparations:
a) hirsutism in women
b) male hypogonadism
c) galactorrhea
d) prostatic hyperplasia
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11
|
Note the main indication for the use of bromocriptine.
a) pituitary insufficiency
b) galactorrhea
c) myxedema
d) to increase lactation in the postpartum period
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16
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What is the name of the type of drug interaction associated with impaired absorption, biotransformation, transport, deposition and excretion of one of the substances?
a) pharmacodynamic interaction
b) functional interaction
c) pharmaceutical interaction
d) pharmacokinetic interaction
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12
|
Specify the mechanism of action of anticoagulants of indirect action:
a) inhibition of the transition of prothrombin to thrombin
b) inhibition of the synthesis of prothrombin and proconvertin in the liver
c) inhibition of the transition of fibrinogen to fibrin
d) dissolution of fibrin clots
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17
|
What effects occur with the use of ganglioblocking agents in therapeutic doses?
a) constriction of the pupils (miosis) and a decrease in intraocular pressure
b) increased skeletal muscle tone
c) tachycardia and increased blood pressure
d) decrease in smooth muscle tone and secretion of the digestive tract
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13
|
Which of the following drugs is an inhibitor of 5-lipoxygenase involved in the synthesis of leukotrienes:
a) prednisolone
b) acetylsalicylic acid
c) zileutin
d) zafirlukast
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18
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What effects occur when using sympathomimetic drugs in therapeutic doses?
a) inhibition of neuromuscular transmission
b) hyperglycemia
c) bradycardia
d) hypotension
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14
|
Specify the drug for the prevention of exacerbation of bronchial asthma, reducing inflammation in the bronchi:
a) cromolyn sodium
b) ipratropium bromide
c) salbutamol
d) eufillin
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19
|
Specify the drug for anesthesia that causes leukopenia, megaloblastic anemia and neuropathy with prolonged inhalation:
a) isoflurane
b) halothane
c) nitrous oxide
d) diethyl ether
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15
|
Specify an analeptic that is a derivative of imidazole dicarboxylic acid diamide:
a) camphor
b) etimizole
c) strychnine
d) bemegrid
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20
|
Specify the characteristic sign of "REM sleep":
a) increased perspiration
b) increased heart rate
c) increased breathing
d) increased eyeball movements
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21
|
Specify what happens to chloride ion channels under the action of barbituric acid derivatives:
a) more frequent opening
b) longer opening
c) partial block
d) full block
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26
|
Specify a non-opioid agent of central action with analgesic activity:
a) reserpine
b) clonidine
c) prazosin
d) anaprilin
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22
|
Specify the side effects that are not typical for long-acting barbituric acid derivatives:
a) material cumulation
b) inhibition of microsomal enzymes
c) development of drug dependence
d) pronounced aftereffect
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27
|
Specify the effect of caffeine on the coronary and cerebral vessels:
a) increase in tone
b) decreased tone
c) increased tone of coronary vessels and expansion of cerebral vessels
d) increased tone of cerebral vessels and expansion of coronary vessels
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23
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Specify an antiparkinsonian drug that inhibits the production of prolactin:
a) cyclodol
b) levodopa
c) Bromocriptine
d) midantane
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28
|
Indicate the mechanism of anticonvulsant action of aminalone:
a) suppression of the effects of excitatory amino acids
) blockade of sodium channels
c) blockade of calcium channels
d) influence on the gamk-ergic system
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24
|
Specify an antipsychotic agent, which has a typical H1-histamine blocking action:
a) haloperidol
b) reserpine
c) chlorpromazine
d) clozapine
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29
|
Specify an analeptic, which may cause the development of tetanic convulsions:
a) strychnine
b) bemegrid
c) cordiamine
d) camphor
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25
|
Specify a drug for the treatment of depression that selectively blocks neuronal serotonin reuptake:
a) fluoxetine
b) maprotiline
c) amitriptyline
d) nialamide
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30
|
Specify an analeptic that is a derivative of imidazole dicarboxylic acid diamide:
a) etimizole
b) camphor
c) strychnine
d) bemegrid
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