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7. Kidney Pain: Blockage of the Urinary System
A blockage of the kidney is a very rare cause of persistent
crying that occurs any time, day or night. Unlike classic colic,
which begins improving after two months, crying from kidney

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pain gets worse and worse.
8. Eye Pain: From Glaucoma to a Corneal Abrasion
Eye pain, also very rare, may come from glaucoma (high
pressure inside the eyeball), an accidental scratch of the cornea,
or even from a tiny, irritating object stuck underneath a baby’s
eyelid (such as an eyelash). Your doctor should consider these
problems if your crying baby has red, tearful eyes and severe
pain that lasts through the day and night.
9. Overdose: From Excessive Sodium to Vitamin A
Persistent, severe crying can result from giving babies
excessive amounts of sodium (salt). This may occur when a
parent mixes formula with too little water. It has also rarely
been described after the first week of life if a breast-feeding
woman is making so little milk that her breast milk becomes
very salty. These babies are easily diagnosed because they are
losing weight, not drinking any other liquids, and are both
irritable and lethargic all day long.
Excess Vitamin A is an extremely rare cause of infant crying.
It only occurs in babies who are given high doses of
supplemental vitamins or fish oil.
10. Others: From Migraines to Heart Failure
Some extraordinarily rare conditions that have been reported
as the cause of unstoppable crying in young infants include: a
bone fracture, sugar intolerance in babies fed fruit or fruit juice,
migraine headache, hyperthyroidism, and heart failure. These
babies don’t merely cry for three hours a day—they act poorly
all day long.

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