Problem The treatment of stenoses of small coronary arteries (svd) and of restenoses after stent deployment (isr) still show unsatisfactory long-term results even after drug-eluting stent deployment


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Problem

  • The treatment of stenoses of small coronary arteries (SVD) and of restenoses after stent deployment (ISR) still show unsatisfactory long-term results even after drug-eluting stent deployment




  • The Paclitaxel-Eluting PTCA-Balloon Catheter in Coronary Artery Disease

  • PEPCAD I-SVD

  • PEPCAD II-ISR







Summary PEPCAD I

  • The paclitaxel-eluting balloon catheter Sequent Please (B.Braun Melsungen AG) …



PEPCAD II Randomized Comparison to Taxus in ISR





As-Treated Groups





Event Free Survival (ITT/As Treated)



Summary PEPCAD II

  • The paclitaxel-eluting balloon catheter Sequent Please (B.Braun Melsungen AG) …

    • was safe and associated with a high procedural success rate in ISR
    • exhibited low late lumen loss after 6 months in ISR
    • was superior to the paclitaxel-eluting Taxus stent in ISR after 6 months
    • has not been associated with late thrombosis in 200 patient years in SVD and ISR


  • Additional Handouts







Contact Information

  • Martin Unverdorben

  • MD, PhD, Associate Professor of Medicine

  •  +1 804 651 3089 (EST)  sbu135@comcast.net




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