Conclusion and future prospects

18. Oral colon cancer targeting by chitosan nanocomposites


Conclusion and future prospects


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Conclusion and future prospects


Chitosan nanocomposite, in the form of nanoparticles, has attracted increasing attention for oral colon cancer targeting due to good biocompatibility, biodegrad- ability, nontoxicity, and anticancer activity. Specifically, these nanoparticles enable increased drug efficacy through promoting drug absorption and bioavailability. Nonetheless, most studies have been conducted in vitro with cell culture system. The in vivo evaluation of nanoparticulate system as oral colon cancer targeting vehicle is still lacking. The appropriateness of chitosan nanocomposite nanoparti- cles as cancer therapeutics carrier for colon cancer treatment requires further tests in vivo.




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