2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry

Scheme 11. Structures and synthetic pathways of potential anti-malaria compounds 30 and 31
Scheme 12. Structures and synthetic route of anti-parasitic compounds 32-35
Scheme 13. Structures and formation of compounds (36-39) with antileishmanial activity
Scheme 14. Structures and synthesis of potential anti-parasitic compounds 40-42
Scheme 15. Structures and synthetic pathways of PTB1B inhibitors 43-46
Scheme 16. Structures and formation of potential anticancer, antimicrobial and anti-influenza agents 47 and 48
Scheme 17. Structure and synthesis of antibacterial and antiviral compound 49
Scheme 18. Synthesis and formation of the A₁AR modulators 68-70
Scheme 19. Structure and synthetic pathway for compound 71
Scheme 20. Structure and synthetic route of compound 72 (NEP28)
Scheme 21. Structure and formation of potential compound 73
Scheme 22. Structure and synthetic route of compound 74
Scheme 23. Structures and synthesis of potential compounds 75 and 76
Scheme 24. Structures and synthesis of potential compounds 77-79
Scheme 25. Structure and synthetic route of compound 80
Scheme 26. Structures and synthetic pathways of compounds 81 and 82
Scheme 27. Structure and synthetic route of potential compound 83
Scheme 28. Structures and synthetic pathways of potential compounds 84 and 85
Scheme 29. Structure and synthetic route of potential compound 89
Scheme 30. Structure and synthetic route of compound 90
Scheme 31. Structure and synthesis of compound 91
Scheme 32. Structures and synthetic route of compounds 91 and 92
Scheme 33. Structure and synthetic pathway of compound 93
Scheme 34. Structure and synthetic route of compounds 95 and 96

1^ Corresponding Author: E-mail: [e-mail] (H. A. Aisa).