Part I: Part I: Principles of Effective Writing Kristin Cobb, Phd principles of Effective Writing


The Scientific Manuscript The Discussion


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The Scientific Manuscript The Discussion

  • 7. Taken together, our findings demonstrate that severely obese subjects with a high prevalence of diabetes and the metabolic syndrome lost more weight during six months on a carbohydrate-restricted diet than on a calorie- and fat-restricted diet. The carbohydrate-restricted diet led to greater improvements in insulin sensitivity that were independent of weight loss and a greater reduction in triglyceride levels in subjects who lost more than 5 percent of their base-line weight. [conclusion; restate answers to a and b] These findings must be interpreted with caution, however, since the magnitude of the overall weight loss relative to our subjects' severe obesity was small, and it is unclear whether these benefits of a carbohydrate-restricted diet extend beyond six months. Furthermore, the high dropout rate and the small overall weight loss demonstrate that dietary adherence was relatively low in both diet groups. [big picture] This study proves a principle and does not provide clinical guidance; given the known benefits of fat restriction, future studies evaluating long-term cardiovascular outcomes are needed before a carbohydrate-restricted diet can be endorsed. [take-home message]

The Scientific Manuscript The Discussion: verb tense

  • Verb Tenses (active!):
  • Past, when referring to study details, results, analyses, and background research:
  • We found that
  • They lost more weight than
  • Subjects may have experienced
  • Miller et al. found
  • Present, when talking about what the data suggest …
  • The greater weight loss suggests
  • The explanation for this difference is not clear.
  • Potential explanations include

The Scientific Manuscript Discussion

  • The Discussion:
  • The answer to the key question asked
  • What’s new
  • The context
    • How your results fit into, contradict, or add to what’s known or believed
  • Strengths and limits of the study
  • The “so what?”: implicate, speculate, recommend
  • Overall conclusion
  • Powerful finish

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