Pharmacology mcqs (final control) 3rd course

= Naltrexone

~ Morphine
~ Disulfiram

110- Which of the following agents may be used as an antidote for ethylene glycol and methanol poisoning?

~ Disulfiram

= Fomepizol

~ Naltrexone
~ Amphetamine
111- The principal mechanism of fomepizol action is associated with inhibition of:
~ Aldehyde dehydrogenase
~ Acethylholinesterase

= Alcohol dehydrogenase

~ Monoamine oxidase

112- Which of the following antipsychotic drugs is typical?

~ Clozapine
~ Quetiapine

= Haloperidol

~ Olanzapine
113- Indicate the atypical antipsychotic drug:
~ Haloperidol

= Clozapine

~ Thioridazine
~ Thiothixene
114- Atypical antipsychotic agents (such as clozapine) differ from typical ones:
~ In reduced risks of extrapyramidal system dysfunction and tardive dyscinesia
~ In having low affinity for D₁ and D₂ dopamine receptors
~ In having high affinity for D₄ dopamine receptors

= All of the above

115- Tardive dyskinesia is the result of:
~ Degeneration of dopaminergic and cholinergic fibers

= Hyperactive dopaminergic state in the presence of dopamine blockers

~ Degeneration of histaminergic fibers
~ Supersensitivity of cholinergic receptors in the caudate-putamen

116- Which of the following antipsychotic drugs has high affinity for D₄ and 5-HT₂ receptors?

= Clozapine

~ Fluphenazine
~ Thioridazine
~ Haloperidole
117- Indicate the antipsychotic drug, which is a phenothiazine aliphatic derivative:
~ Thiothixene
~ Risperidone

= Chlorpromazine

~ Clozapine

118- Indicate the antipsychotic drug having significant peripheral alpha-adrenergic blocking activity:

~ Haloperidol