Pharmacology mcqs (final control) 3rd course

= Antiprogestin

~ Antiandrogen
~ Antiestrogen
~ Androgen

249. 
     Mifepristone (RU-486) is used as a contraceptive and abortifacient. This consideration is:
     

= True

~ False

249. 
     Actions of mifepristone (RU-486) include:
     

~ Inhibition of ovulation during the follicular phase by blocking hypothalamic-pituitary progesterone receptors, which suppresses midcycle gonadotropin release
~ During the luteal phase, inhibition of progesterone action on the uterus, which induces prostaglandin release from the endometrium
~ Termination of pregnancy by facilitating luteolysis, menstruation, uterine motility, softening of the cervix, and detachment of the embryo.

249. 
     bIndicate a cholinomimetic agent, which is related to direct-acting drugs:
     

~ Edrophonium
~ Physostigmine

= Carbachol

~ Isoflurophate

249. 
     Characteristics of carbachol include all of the following EXCEPT:
     

~ It decreases intraocular pressure

= It causes mydriasis

~ It exerts both nicotinic and muscarinic effects
~ It is resistant to acethylcholiesterase

249. 
     Acetylcholine is not used in clinical practice because:
     

~ It is very toxic
~ The doses required are very high

= It is very rapidly hydrolyzed

~ It is very costly

249. 
     Parasympathomimetic drugs cause:
     

~ Bronchodilation
~ Mydriasis

= Bradycardia

~ Constipation

249. 
     Which of the following direct-acting cholinomimetics is mainly muscarinic in action?
     

= Bethanechol

~ Carbachol
~ Acetylcholine
~ None of the above

249. 
     Which of the following direct-acting cholinomimetics has the shortest duration of action?