Unit 1 Description of a Pharmacy Grammar


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DEXONA INJECTION

Dexamethasone Sodium Phosphate is a water soluble inorganic ester of dexamethansone.



PRESENTATION:

Each ml. of Dexona Injection 2 ml. Vial contains 4.4 mg of Dexamethasone Sodium Phosphate U.S.P. (as the disodium salt) equivalent to 4 mg of Dexamethasone.



PHARMACOLOGY:

Dexamethasone is a synthetic adrenocortical steroid possessing basic glucocorticoid actions and effects. It is among the most active members of its class, being about 25 to 30 times as potent as hydrocortisone. At equivalent anti-inflammatory doses, dexamethasone almost completely lacks the sodium retaining property of hydrocortisone and closely related derivatives of hydrocortisone. Dexona produces rapid response when compared with less soluble preparations. Plasma steroid levels increase noticeably within five minutes after intramuscular or intravenous injection. Dexona is primary used for its potent anti-inflammatory effects in disorders of many organ systems. In addition, it modifies body’s immune response to diverse stimuli.




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