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INTRODUCTION (abstract of DSc thesis)
The urgency and relevance of the dissertation topic. According to the
World Health Organization cerebral stroke is a
major cause of mortality in
developed countries, and in the structure of total mortality takes 2-3 position. The
total number of patients with stroke or transient ischemic attacks in the anamnesis
in the world more than 50 million. Ischemic stroke (IS) - Important medical and
social problem and a
major cause of hospitalization, disability and mortality in
developed countries. In despite of the close attention of
scientists and specialists
around the world the problem of early diagnosis of ischemic stroke and adequate
cerebral reperfusion remains topical.
The aim of research work is development of radial methods of prediction
of ischemic stroke flow depending on neuroimaging and hemodynamic patterns in
the acute phase of the disease.
The tasks of research :
to complement the criteria of embologenity of
atherosclerotic plaques and
evaluate relationship with the size of focus of cerebral ischemia;
to study the echocardiographic
changes in ischemic stroke;
to develop optimal criteria for the allocation of patterns of intracranial
hemodynamics;
to investigate the character of cerebral hemodynamics
and the state of
cerebrovascular reactivity in patients with ischemic stroke;
to conduct a Doppler sonography and neuroimaging comparison depending
on the pattern of intracranial hemodynamics and ischemic
focus size;
to evaluate the effectiveness of thrombolytic therapy from the position
ultrasound methods.
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