Biology E/M Subject Test
271
ARCO
■
SAT II Subject Tests
w w w . p e t e r s o n s . c o m / a r c o
26. The correct answer is (B). An X-linked gene signifies that such a gene is sex-linked and occupies a
locus on the X sex chromosome. Furthermore, since the
gene in question is dominant, one “dose” of
this gene will allow its full expression. (This is in contrast to a recessive gene, which requires the
absence of the dominant gene in order for it to be expressed.) If X*
is allowed to represent the
particular dominant, X-linked gene in question, the
mating can be described as
XX
x
X*Y
unaffected female
affected male
Note that the female has to be XX and cannot be X*X or X*X*. Why? Realize that X*X or X*X* would
signify an affected female–the X* is dominant! Hence, an unaffected female could not possess this gene.
In addition, if it is assumed that the carrier state represents an individual
who possesses the gene in
question but is not affected, there can be no carriers for this gene. That is, each offspring who possesses
the X* gene will be affected. Arranging a Punnett square for the cross
that occurs in this problem, then:
So, 100% of the female offspring will inherit the X* chromosome. However, the X chromosome of
the male offspring will be one of the unaffected X chromosomes from the unaffected female parent.
Hence, none of the males will be affected.
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