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HPLC method for det ermination of lamotrigine impuriities in Lamal® tablets……...........209-210
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HPLC method for det ermination of lamotrigine impuriities in Lamal® tablets……...........209-210 I. Bo`inovska, D. Kafexiska, C. Doli}oska, M. Simjanovska, B. Samarova - Stoev, B. [apkareva, H. Babunovska Odreduvawe na srodni i degradacioni produkti na Lamotrigin vo Lamal® tableti so HPCL metoda PP - 99 K. Brzilova, H. Babunovska, V. Dubrova -Koceva, S. Janeva, D. Damcevska, B. Debarlieva, F. Butikoski, T. Kovacevik -Novakova Forced degradation study performed on Lisinopril dihydrate active pharmaceutical ingredient………………………………………………………………211-212 K. Brzilova, H. Babunovska, V. Dubrova -Koceva, S. Janeva, D. Dam~evska, B. Debarlieva, F. Butikoski, T. Kova~evi} -Novakova Forsirana degradaciona studija izvr{ena vrz aktivnata supstanca Lisinopril dihydrate PP - 100 G. Evgenievska1, S . Naumovska, S. Sardzovska, L. Markovska, A. Jovanovic, H. Babunovska, B. Sapkareva and J. Bogdanov Determination of impurity profile of morphine hydrochloride by HPCL with diode array detector…………………………………………..21 3-214 G. Evgenievska1,, S. Naumovska, S . Sarxovska, L. Markovska, A. Jovanovi}, H. Babunovska, B. [apkareva i J. Bogdanov Odreduvawe na profil na one~istuvawa na morfin hidrorohlorid so HPLC-DAD PP - 101 Katerina Kocova, Lidija Mano Iliev, Irina Batkovska Borozanova, Gordana Trendovska Serafi movska RP- HPLC gradient metod for simultaneous quantification of Salbutamol sulphate and preservatives in pharmaceutical dosage forms…..……………2 15-216 Katerina Ko~ova, Lidija Mano Iliev, Irina Batkovska Borozanova, Gordana Trendovska Serafimovska Reverzno Fazen HPLC-gradient metod za simultana kvantifikacija na Salbutamol sulfat i konzervansi vo farmacevtski doza`ni formi xvii ^ETVRTI KONGRES NA FARMACIJATA NA MAKEDONIJA SO ME\UNARODNO U^ESTVO FOURTH CONGRESS OF PHARMACY OF MACEDONIA WITH INTERNATIONAL PARTICIPATION PP - 102 Piponski M., Slaveska I., Rusevska T., Mindoseva M., Serafimovska -Trendovska G., Simoultaneous quantitative determination of 2 active components and 2 preservatives in liquid dosage form trimosul with HPLC……………………...….…..2 17-218 Piponski M., Sla veska I., Rusevska T., Mindoseva M., Serafimovska -Trendovska G. Simultano kvantitativno odreduvawe na 2 aktivni komponenti i 2 konzervansi vo te~na doza`na formulacija na Trimoksazol so HPLC metoda PP - 103 Piponski M., Rusevska T., Slaveska I., Hristova O. , Serafimovska -Trendovska G. Development of HPLC method for simoultaneus quantification of dexchlorfeniramine, paracetamol, pseudoephedrine and dextrometorphan in solid pharmaceutical dosage forms…………………………….….2 19-220 Piponski M., Rusevska T., Slave ska I., Hristova O., Serafimovska -Trendovska G. Razvoj na izokratska HPCL metoda za simultana kvantifikacija na Dexchlorfeniramine, Paracetamol, Pseudoephedrine i Dextrometorphan vo cvrsti farmacevtski dozazni formi PP - 104 Vasil Karcev, Lence Nikolova, Liljana Ugrinova, Suzana Trajkovic -Jolevska Determination of benzalkonium chloride in pharmaceutical by UV-spectrophotometry…………………….….……………………………………………..22 1-222 Vasil Kar~ev, Len~e Nikolova, Liljana Ugrinova, Suzana Trajkovi} -Jolevska Opredeluvawe na be nzalkonium hlorid vo farmacevtski preparat so UV-spektrofotometriski metod PP - 105 N. Stojanoska, B. Krstevska, V. Ajanovska, Z. Mironovski, J. Velevska, H. Babunovska Identification of metamizole sodium with the nirs (Near Infrared Spectroscopy) metho d…………………….….………………………………..22 3-224 N. Stojanoska, B. Krstevska, V. Ajanovska, Z. Mironovski, J. Velevska, H. Babunovska Identifikacija na Metamizole sodium so NIRS (Near Infrared Spectroscops metod PP - 106 Sober M., Marjanovic A., Djedjibegovic J., Skr bo A., Bilalagic N. Sensitized luminescence of lanthanides as an analitical tool in Clarithromycin determination…………………….…………………………………………..….2 25 PP - 107 S. Apostolovska, A. Dimitrovska, V. Karcev Spectrpophotometric determinarion of Thiomersal in eye pr eparations……………....…….226-227 S. Apostolovska, A. Dimitrovska, V. Kar~ev Spektrofotometrisko opredeluvawe na Tiomersal vo oftalmolo{ki preparati PP - 108 Maja Velichkovska, Vasil Karcev, Liljana Ugrinova, Aneta Dimitrovska Determination of Allantoin in Cosmetical and Pharmaceutical products by spectrophotometric method in visible region ….………….……………………………….2 28-229 Maja Veli~kovska, Vasil Kar~ev, Liljana Ugrinova, Aneta Dimitrovska Opredeluvawe na alantoin vo farmacevtski i kozmeti~ki preparati so spektrofotometriski metod vo vidlivo podra~je PP - 109 Gorica Vukovic, MarinelaTadic, Marija Saric Determination of UV protection substances in cosmetic products by RP - HPCL with UV - DAD detection…………………….…….……….230 PP - 110 E. Popovska, S. Ilioska Zlat anovik, H. Babunovska, V. Jovanovska, M. Ilievska Validation and quantitative detection of bacterial endotoxins with kinetic turbidimetric method on Heparin inj. 5000 IU/ml…………………….……….….….23 1-232 E. Popovska, S. Ilioska Zlatanovik, H. Babunovska, V. Jov anovska, M. Ilievska Validacija i kvantitativno odreduvawe na bakteriski endotoksini so kineti~ko turbidimetriska metoda na preparatot Heparin inj. 5000 IE/ml PP - 111 Ljiljana Krsteska, J. Dimitrovska,S. M. Sejfulah , Sonja Ugarkovic Efficacy of antimicr obial preservation in Pholcodin 15 mg/15 ml oral solution…………….23 3-234 Qiqana Krsteska, J. Dimitrovska, S. M. Sejfulah, S. Ugarkovi} Antimikrobna efikasnost na konzervansi vo Pholcodin rastvor 15mg/15 ml rastvor za oralna upotreba xviii ^ETVRTI KONGRES NA FARMACIJATA NA MAKEDONIJA SO ME\UNARODNO U^ESTVO FOURTH CONGRESS OF PHARMACY OF MACEDONIA WITH INTERNATIONAL PARTICIPATION PP - 112 Dzenita Softic, Diana Jerg -Simanovc, Tamara Bosnic, Vesna Simic Evaluation of the microbiological quality of medicines prepared in pharmacies………….….….2 35 PP - 113 A. Isovic, M. Mihajljica, S. Caklovica Storage time influence on purified water Bio burden ……..……………………………………….236 PP - 114 Vid Stanulovic Safety Monitoring in Pre -marketing Trials……..…………………………………………….…….237 PP - 115 Minela Dobojak, Maja Hadzihasanovic, Elma Obradovic, Majda Prcic, Midhat Vehabovic Lifecycle of Variation Management bef ore submission to the Regulatory Authorities – Practical solution……..……………………………………….…..238 PP - 116 Amra Begovic, Katerina Maceva, Lejla Sadovic, Midhat Vehabovic, Aida Lihic, Mare Akimovska Harmonisation labelling and package leaflet with EU requirement s………………………….….239 PP - 117 Slobodanka Simic, Ljiljana Petrovic, Mirjana Rajic, Svetlana Trajkovic Out of specification results - causes and levels of responsibility……..………………………….....240 PP - 118 Ivana Mihajlovic, Gordana Mihajlovic Medicinal products appr oved for use in Serbia……..……………………………………………..24 1 PP - 119 Ivana Mihajlovic Antiepileptic approved for use in Serbia…………………………………………..…………….….2 42 PP - 120 Adela Alomerovic, Amela Dervisevic, Alma Jasar Comparative analysis of regulatory requirements in t he Federation of Bosnia and Herzegovina and Republic of Srpska……………………………...…...2 43 PP - 121 Zorica Arsova -Sarafinovska, Liljana Ugrinova, Katerina Starkoska, Dragan Djordjev, Aneta Dimitrovska HPLC method with UV and fluorescence detection for determinati on of ethinylestradiol and drospirenone in oral contraceptive tablets..……..…… …………........244-245 Zorica Arsova -Sarafinovska, Liljana Ugrinova, Katerina Starkoska, Dragan \or|ev, Aneta Dimitrovska HPLC metod so UV i fluorescentna detekcija za opredeluvawe na etinilestradiol i drospirenon vo peroralni kontraceptivni tableti PP - 122 Katerina Ancevska Netkovska, Jadranka Dabovik Anastasovska The importance of legal protection of intellectual property rights in the pharmaceutical industry in the RM……..……………………………………………...2 46-247 Katerina An~evska Netkovska, Jadranka Dabovi} Anastasovska Zna~eweto na pravnata za{tita na pravata od intelektualna sopstvenost vo farmacevtskta industrija vo RM PP - 123 N. Zdravkovska, M Kova~eva, L. Petru{evska -Tozi Kontinuirana ta edukacija na diplomiranite farmacevti vo pravnata regulativa na Republika Makedonija ……..………………………………...….2 48 KLINI^KA BIOHEMIJA I TOKSIKOLOGIJA CLINICAL BIOCHEMISTRY & TOXICOLOGY SPL - 12 Filiz HINCAL Safety issues in drug therapy and the rol e of pharmcist……………………………………..…….2 50 SPL - 13 Z. Kavrakovski, K. Mladenovska, L. Petrusevska -Tozi The Macedonian poison control center - vision or necessity………….…………………….....251-252 Z. Kavrakovski, K. Mladenovska, L. Petru{evska -Tozi Centar za kontrola na truewa vo Republika Makedonija - vizija ili potreba SPL - 14 Tatjana Kadifkova Panovska and Svetlana Kulevanova Reactive Oxigen Species and Defense Systems………….……………………………………..2 53-254 Tatjana Kadifkova Panovska i Svetlana Kulevanova Reaktivni kislorodn i vidovi i odbranbeni sistemi KLINI^KA BIOHEMIJA I TOKSIKOLOGIJA CLINICAL BIOCHEMISTRY & TOXICOLOGY xix ^ETVRTI KONGRES NA FARMACIJATA NA MAKEDONIJA SO ME\UNARODNO U^ESTVO FOURTH CONGRESS OF PHARMACY OF MACEDONIA WITH INTERNATIONAL PARTICIPATION PP - 124 Ksenija Mickova Dimitrova, Lidija Petrushevska -Tozi, Igor Kuzmanovski, Zoran Kavrakovski C lassification of endocrine disrupters using supervised self -organizing maps……….….….255-256 Ksenija Mickova Dimitrova, Lidija Petru{evska -Tozi, Igor Kuzman ovski, Zoran Kavrakovski Klasifikacija na hemikalii koi ja poremetuvaat funkcijata na endokriniotsistem so upotreba na samoorganizirani mapi PP - 125 Cekovska Svetlana, Palchevska Snezhana, Velibor Tasik, Korneti Petar Urinary proteins in febrile conditi ons of non renal origin………….………………………...2 57-258 Cekovska Svetlana, Pal~evska Sne`ana, Velibor Tasi}, Korneti Petar Urinarni proteini kaj febrilni sostojbi od nerenalno poteklo PP - 126 T. Gruev, M. Bogdanova, K. Chakalarovski, L. Petrushevska -Tozi Serum Cystatin C concentracion in transplanted patients treated with glucocorticoid immunosuppression………… …………………………………….. .…….259-260 T. Gruev, M. Bogdanova, K. ^akalarovski, L. Petru{evska -Tozi Koncentracija na Cistatin C kaj transplantirani pacienti tretirani so glukokortikoidnata imunosupresivna terapija PP - 127 Z. Mandinic, M. Curcic, B. Antonijevic, M. Nedeljkovic, M. Carevic Fluoride Levels in Enamel Samples of Children from Fluorotic Region of Vranje…………..….2 61 PP - 128 Marijana Curcic Jovanovic, Mir jana Djukic, Milica Ninkovic, Ivana Maksimovic, Marina Jovanovic Involvement of NMDA receptors in diquat neurotoxicity………….………………………….…..2 62 PP - 129 Suzana Angelova, Desa Jakimova, Lidija Petrusevska -Tozi Determination of diazepam in serum by GC - ECD………….………………………………..263-264 Suzana Angelova, Desa Jakimova, Lidija Petru{evska -Tozi Primena na gasna hromatografija so ECD detekcija vo opredeluvawe na diazepam vo serum PP - 130 R. Gosevska, M. Sudzukovic, E. Bagasovska Relationship between lipoprotein le vels and antioxidant capacity in patients with coronary heart disease………….……………………………………………..2 65-266 R. Go{evska, M. Su|ukovi}, E. Baga{ovska Vrskata pome|u lipoproteinskiot status i antioksidantniot kapacitet kaj pacienti so koronarni srcevi zaboluvawa PP - 131 Rade Injac, Marija Boskovic, Vukosava Djordjevic -Milic, Borut Strukelj, Aleksandar Djordjevic, Biljana Govedarica, Natasa Radic, Martina Perse, Anton Cerar Activity of enzymes in serum during doxorubicine single dose therapy of malign neoplasma in rats pretreated by fullerenol C 60 (OH) 24 ……………………….………..267 PP - 132 Vukosava Djordjevic -Milic, Viktorija Dragojevic -Simic, Biljana Govedarica, Natasa Radic, Rade Injac, Branislava Srdjenovic, A. Djordjevic, V. Vasovic The effect of fullerenol on antiox idative status of heart in rats after single dose administration of doxorubicin………….………………………………………....2 68 HERBALNI MEDICINSKI PROIZVODI, HRANA I ISHRANA HERBAL MEDICINAL PRODUCTS, FOOD AND NUTRITION SPL - 15 Roberrto Della Logia Anti-inflammatory plants in practical phytotherapy……………………………………………....27 0 SPL - 16 Nada Kovacevic Modern Research in Pharmacognosy; Morphological, Chemical and Pharmacological Characterization of Herbal Drugs………………………………..…….…....27 1 SOP - 6 Svetlana Kulevanova,Tatj ana Kadifkova Panovska The Health Benefits of Tea……………………………………………………………… ……....272-273 Svetlana Kulevanova, Tatjana Kadifkova Panovska Pridobivki vrz zdravjeto od upotrebata na ~ajot HERBALNI MEDICINSKI PROIZVODI, HRANA I ISHRANA HERBAL MEDICINAL PRODUCTS, FOOD AND NUTRITION xx ^ETVRTI KONGRES NA FARMACIJATA NA MAKEDONIJA SO ME\UNARODNO U^ESTVO FOURTH CONGRESS OF PHARMACY OF MACEDONIA WITH INTERNATIONAL PARTICIPATION SOP - 7 L. Petrusevska -Tozi, K. Mladenovska Probiotic functional food in improving gut health……………………………...……...…..….27 4-275 L. Petru{evska -Tozi, K. Mladenovska Uloga na funkcionalnata probiotska hrana vo podobruvawe na ~ovekovoto zdravje SOP - 8 Gjoshe Stefkov, Todor Gruev, Svetlana Kulevanova Biochemical assessment of the toxicity to liver, hearth and kidneys of Teucrium polium extracts in the treatment of diabetic rats…………………………….….2 76-277 \o{e Stefkov, Todor Gruev, Svetlana Kulevanova Biohemiska procenka na toksi~nosta vrz funkcijata na crniot drob, srceto i bubrezite na ekstrakti od Teucrium polium pri tretman na dijabeti~ni staorci SOP - 9 Biljana Bauer Petrovska, Mitko Karadelev, Svetlana Kulevanova Medicinal mushrooms as a source of biolo gical active compounds and their beneficial impact on health……….…………………… ………………………... ….278-279 Biljana Bauer Petrovska, Mitko Karadelev, Svetlana Kulevanova Medicinski gabi kako izvor na biolo{ki aktivni komponenti i nivno korisno vlijanie vrz zdravjet o SOP - 10 Mitko Karadelev, Sami Sulejmani , Biljana Bauer Petrovska Distribution and Ecology of Human -Toxic Macromycetes in the Republic of Macedonia..……......280-281 Mitko Karadelev, Sami Sulejmani , Biljana Bauer Petrovska Distribucija i ekologija na hu mano-toksi~ni makromiceti vo Republika Makedonija PP - 133 A. Novakovic, M. Peric, D. Nezic, Lj. Gojkovic Bukarica The Effect of Wine Polyphenol Resveratrol on the Isolated Human Internal Mammary Artery……………………………………………………….……..….28 2 PP - 134 Elizabeta Markoska, Ana Petkovska, Mirko Spasenoski, Marina Stefova, Sonja Gadzovska Secondary metabolite production in Astragalus parnassi Boiss. plant…….……………….….….28 3 PP - 135 Milica Pavlovic, Marina Milenkovic, Jelena Antic Stankovic, Maria Couladis, Olga Tza kou, Nada Kovacevic Chemical composition and antimicrobial activity of the essential oil of Trinia glauca…....……..28 4 PP - 136 Silvana Petrovic, Milica Pavlovic, Marina Milenkovic, Maria Couladis, Olga Tzakou, Zoran Maksimovic, Marjan Niketic Composition and antimicrobial activity of Marrubium incanum essential oil ………..….……...285 PP - 137 D. Djukic-Cosic, Z. Plamenac Bulat, M. Curcic Jovanovic, A. Stanojevic, M. Djekic, I. Djuric, Z. Zoricic, V. Matovic Cadmium content in Hypericum perforatum L. grown in different areas of Serbia………...…...2 86 PP - 138 Dzenita Softic, Sasa Pilipovic, Amar Elezovic Importance of researches on aflatoxins presence in herbal drugs………. .……………………….287 PP - 139 Ilina Krasteva, Georgi Momekov, Spiro Konstantinov and Stefan Niko lov Cytoprotective effects of a new flavonoid from Astragalus hamosus ………………....….…. …288 PP - 140 Petranka Zdraveva, Ilina Krasteva, Ivanka Pencheva, Stefan Nikolov Phytochemical investigation of Astragalus cicer L. (Fabaceae) ………………………...…....… 289 PP - 141 Tatjana Kadifkova Panovska, Svetlana Kulevanova, Icko Gjorgoski, Mirjana Bogdanova, Gordana Petrushevska Prophilactic effect of Urtica dioica seed extrats against acute experimental hepatotoxicit in vivo……………………………….....……….…..290-291 Tatjana Kadifk ova Panovska, Svetlana Kulevanova, Icko \orgoski, Mirjana Bogdanova i Gordana Petru{evska Za{titen efekt na ekstrakti od seme na Urtica dioica nasproti akutna eksperimentalna hepatotoksi~nost in vivo xxi ^ETVRTI KONGRES NA FARMACIJATA NA MAKEDONIJA SO ME\UNARODNO U^ESTVO FOURTH CONGRESS OF PHARMACY OF MACEDONIA WITH INTERNATIONAL PARTICIPATION PP - 142 Tatjana Kadifkova Panovska, Svetlana Kulevanova, Icko Gjorgoski, Mirjana Bogdanova, Gordana Petrushevska Evaluation of the antioxidant and hepatoprotektive effect of Helychrisum plicatum extracts……………………...……...….… …………………………292-293 Tatjana Ka difkova Panovska, Svetlana Kulevanova, Icko \orgoski, Mirjana Bogdanova, Gordana Petru{evska Procenuvawe na antioksidativniot i hepatoprotektivniot efekt na ekstraktite od Helychrisum plicatum PP - 143 Tatjana Kadifkova Panovska, Svetlana Kulevanova, I cko Gjorgoski, Mirjana Bogdanova, Gordana Petrushevska Studies on the preventive effect of Micromeria cristata extracts on fatty liver development by carbon tetrachloride in rats…...……...… ………………...….294-295 Tatjana Kadifkova Panovska, Svetlana Kulevan ova, Icko \orgoski, Mirjana Bogdanova, Gordana Petru{evska Studii za preventivniot efekt na ekstraktite od Micromeria cristata vrz razvojot na masen crn drob kaj CCl4 tretirani staorci PP - 144 Flurim Nebija, Gjose Stefkov, Marija Karapandzova, Bilja na Bauer Petrovska, Svetlana Kulevanova Defining of the morphological - anatomical markers for identification of root and herb from Eryngium campestre L. (Apiaceae)…...……...….… …………….. ……… ……….…………. .296-297 Flurim Nebija, \o{e Stefkov, Marija Karapanxova, Biljana Bauer Petrovska, Svetlana Kulevanova Definirawe na morfolo{ko -anatomskite markeri za identifikacija na koren i herba od Eryngium campestre L. (Apiaceae) PP - 145 Flurim Nebija, Gjose Stefkov, Marija Karapandzova, Svetlana Kulevanova Marina Stefov a HPLC metod for identification and determination of flavonoids in Eryngii herba (Eryngium campestre L., Apiaceae)…...……...… ………………………..….298-299 Flurim Nebija, \o{e Stefkov, Marija Karapanxova, Svetlana Kulevanova, Marina Stefova Voveduvawe na HPLC metod za identifikacija i opredeluvawe na flavonoidi vo Eryngii herba (Eryngium campestre L., Apiaceae ) PP - 146 Gjoshe Stefkov, Marina Stefova, Svetlana Kulevanova Localization and variability of flavon aglycons in Teucrium polium from different localit ies of the Republic of Macedonia…...…… ……………………... .….….300-301 \o{e Stefkov, Marina Stefova, Svetlana Kulevanova Lokalizacija i varijabilnost na flavonskite aglikoni vo Teucrium polium od razli~ni regioni na Republika Makedonija PP - 147 Gjoshe Stefkov, Gordana Petrusevska, Svetlana Kulevanova Histomorphological assessment of the toxicity to liver, myocardial and renal tissue of the Teucrium polium extracts in the treatment of diabetic rats… ......….302-303 \o{e Stefkov, Gordana Petru{evska, Svetlana K ulevanova Histomorfolo{ka procenka na toksi~nosta vrz crniot drob, srceto i bubrezite na ekstrakti od Teucrium polium pri tretman na dijabeti~ni staorci PP - 148 Gjoshe Stefkov, Anna Jager, Per Molgaard, Knud Josefsen, Svetlana Kulevanova In vitro inve stigation of the insulinotropic effect of several flavonoids in INS-1E insulinoma cells…...……...….… …………………………………………………...304-305 \o{e Stefkov, Knul Jozefsen, Ana Jager, Pjer Molgard, Svetlana Kulevanova In vitro ispituvawe na insulinotropniot efekt na opredeleni flavonoidi kaj INS-1E kletki PP - 149 Gjoshe Stefkov, Anna Jager, Per Molgaard, Knud Josefsen, Svetlana Kulevanova In vitro investigation of the insulinotropic effect of the Teucrium polium extracts in INS -1E insulinoma cells…...……..........................................…….306-307 \o{e Stefkov, Knul Jozefsen, Ana Jager, Pjer Molgard, Svetlana Kulevanova In vitro ispituvawe na insulinotropniot efekt na ekstrakt Download 4.82 Kb. 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