Қонда глюкоза миқдорининг бошқарилиши

Mavzu: Glyukoza metobilizmi va qonda glyukoza miqdorining boshqarilishi 2 kurs Biologik kime dotsent M.U.Kulmanova

Kоrib chiqiladigan savollar

• 1.Glyukoza katobolizmi. Aerob glikoliz.
• 2.Mokki mexanizmi.
• 3.Anaerob glikoliz.
• 4.Glyukoneogenez
• 5.Glikoliz va glyukonegenezni kalit fermentlari.
• 6.Fruktoza va galaktoza almashinuvi
• 7.Glyukozaning pentoz-fosfat yоlida oksidlanishi, uning ahamiyati
• 8.Qonda glyukoza miqdorining boshqarilishi
• 9.Glikoproteinlar va proteoglikanlar tоgrisida tushuncha

• The pentose phosphate pathway (also called the hexose monophosphate shunt, or pathway) occurs in the cytosol of the cell. consists of two, irreversible oxidative reactions, followed by a series of reversible sugar-phosphate interconversions

• The oxidative portion of the pentose phosphate pathway consists of three reactions that lead to the formation of ribulose 5-phosphate, and two molecules of NADPH for each molecule of glucose 6-phosphate oxidized

• The nonoxidative reactions of the pentose phosphate pathway occur in cell types synthesizing nucleotides and nucleic acids. These reactions catalyze the interconversion of three-, four-, five-, six-, and sevencarbon sugars

• Glycosaminoglycans (GAGs) are large complexes of negatively charged heteropolysaccharide chains

Glyukozani aerob oksidlanishi

• Glyukozani aerob oksidlanishi SO2 va N2O. :
• S6N12O6 Q 6O2 → 6SO2Q 6N2O Q 2880 kDjG’mol.
• Bu jarayeni bir necha bosqichda amalga oshadi:
• Aerob glikoliz. 1 glyukozadan 2 piruvat, 2 ATF va 2 NADN2 ;
• 2 piruvat oksidlanib dekarboksilanib 2 atsetil-KoA , 2 SO2 va 2 NADN2;
• Uchkarbon kislotalar sikli. 2 atsetil-KoA , 4 SO2, 2 GTF (2 ATF), 6 NADN2 va 2 FADN2;
• Nafas zanjirida. 10 (8) NADN2, 2 (4) FADN2 va 6 N2O.