International conference on bioinformatics of genome regulation

  
A. Ito, S. Hano, N. Imoto, T. Shibuya, Y. Kanayama 
105
NOVEL APPROACH FOR COMPUTATIONAL DESIGN OF SMALL MOLECULE INHIBITORS  
OF PROTEIN/PROTEIN INTERACTIONS IN CD95/FAS PATHWAY 
 
N.V. Ivanisenko, A.S. Ishchenko, I.N. Lavrik, V.A. Ivanisenko 
106
POLYMORPHISM OF LOXL1 GENE IN WEST SIBERIA PATIENTS WITH OPEN ANGLE GLAUCOMA AND 
PSEUDOEXFOLIATION GLAUCOMA.   
D.E. Ivanoshchuk, E.O. Datskih, N.A. Konovalova, I.Y. Bychkov, A.Z. Fursova, O.S. Konovalova,  
S.V. Mikhailova , M.N. Ponomareva, M.I. Voevoda, A.G. Romaschenko 
107
IDENTIFICATION OF PROTEINS ASSOCIATED WITH DRUG-INDUCED LIVER INJURY  
USING IN SILICO PREDICTION OF DRUG-TARGET INTERACTIONS
 
S.M. Ivanov, M.I. Semin, A.A. Lagunin, D.A. Filimonov, V.V. Poroikov
 
108
USING THE BIOINFORMATIC SOFTWARE TECHNICUES TO SEARCH CRISPR / CAS 

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
SYSTEMS IN THE GENOME OF ESCHERICHIA COLI STRAIN O157:H7
 
E.I. Ivanova, Yu.P. Dzhioev, A.Yu. Borisenko, A.I. Paramonov, V.I. Zlobin, N.L. Belkova
 
109
MIR-619-5P BINDING SITES IN PROTEIN CODING REGION OF ORTHOLOG GENES MRNA
 
A.T. Ivashchenko, S.A. Atambayeva, R.E. Niyazova, A.Y. Pyrkova 
110
FEATURES OF MIRNA INTERACTION WITH MRNA GENES IN CORONARY HEART DISEASE 
A.T. Ivashchenko, R.E. Niyazova, S.A. Atambayeva, A.Y. Pyrkova 
111
SEX CHROMOSOME EVOLUTION IN PAMPHAGIDAE GRASSHOPPERS 
I.E. Jetybayev, A.G. Bugrov, O.G. Buleu, A.G. Bogomolov, N.B. Rubtsov
 
112
DNA REPAIR AND DEATH SIGNALING TARGETED BY ALKYLATING ANTICANCER DRUGS
 
B. Kaina 
113
FUNCTIONAL ANALYSIS OF RNA-SEQ TRANSCRIPTOMES FROM OESOPHAGEAL  
CANCER SPECIMENS OF KAZAKHSTANI PATIENTS
 
U. Kairov, A. Molkenov, S. Rakhimova, A. Abilmazhinova, M. Zhalbinova, D. Yerezhepov, 
A. Akhmetova, Y. Zhukov, M. Omarov, M. Popova, A. Zinovyev, A. Akilzhanova, Zh. Zhumadilov
 
114
DIVERGENCE OF PARALOGOUS GROWTH HORMONE GENES IN SALMONIDS
 
D.N. Kamenskaya, M.V. Pankova, D.M. Atopkin, V.A. Brykov
  
115
DINAMIC METBOLIC REGULATION BY A CHROMOSOME SEGMENT FROM A WILD  
SPECIES DURING FRUIT DEVELOPMENT IN A TOMATO INTROGRESSION LINE 
 
Y. Kanayama 
116
BASED ON THE LOCAL SEQUENCE SIMILARITY METHOD FOR PREDICTION  
OF AMINO ACID POSITIONS RELATED TO THE PROTEIN-LIGAND SPECIFICITY 
 
D.A. Karasev, A.V. Veselovsky, N.Yu. Oparina, A.V. Rudik, D.A. Filimonov, B.N. Sobolev 
117
SEQUENCING FROM ROCHE: WHAT THE FUTURE WILL BRING FOR YOU?
 
I.Y. Karpova 
118
BIOMOLECULAR SYSTEMS MODELS SEMI-AUTOMATIC RECONSTRUCTION BASED  
ON STRUCTURAL AND QUANTITATIVE INFORMATION
 
F.V. Kazantsev, I.R. Akberdin, S.A. Lashin, N. Ree, V. Timonov, A.V. Ratushny,  
T.M. Khlebodarova, V.A. Likhoshvai 
119
REGULATORY ROLE OF SINGLE CPG METHYLATION
A. Khamis, A.V. Artemov, A.V. Lioznova, V.B. Bajic, Y.A. Medvedeva 
120
GENETIC DIVERSITY IN NATIVE SIBERIAN POPULATIONS: CORRELATION WITH  
CLIMATIC AND GEOGRAPHICAL PARAMETERS 
 
V.N. Kharkov, A.V. Markov, I.Yu. Khitrinskaya, V.A. Stepanov
 
121
THE INFLUENCE OF RARE MUTATIONS IN THE APOB GENE TO THE LEVEL OF OXIDIZED LDL
 
E.Yu. Khlebus, N.V. Shcherbakova, I.S. Zhanin, A.A. Zharikova, A.I. Ershova,  
A.V. Kiseleva, S.A. Boytsov, A.N. Meshkov  
122
WHAT WE USUALLY STUDY WHEN WE THINK WE STUDY AGING 
 
A.N. Khokhlov 
123
THE FIRST EDITION OF MUTAGENESIS BY CRISPR/CAS IN THE EXTREME DESICCATION  
TOLERANT CULTURED CELL 
 
T. Kikawada, Y. Miyata, Y. Sogame, T. Furusawa, S. Kikuta, R. Cornette, O. Gusev  
124
ANHYDRO-PRESERVATION OF EXOGENOUSLY-EXPRESSED DESICCATION-SENSITIVE 
ENZYME LUCIFERASE USING INSECT CELLS
 
S. Kikuta, S. Watanabe, O. Gusev, Y. Sogame, R. Cornette, T. Kikawada
 
125
MOLECULAR DYNAMICS CHARACTERIZATION OF GLYCYRRHIZIN INTERACTION 
 WITH LIPID MEMBRANES
 
A.V. Kim, E.A. Shelepova, N.N. Medvedev 
126

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
GENOMEASIA 100K INITIATIVE ANNOUNCED TO SEQUENCE 100,000 GENOMES  
IN SOUTH, NORTH AND EAST ASIA
 
H.L. Kim, E.S. Gusareva, S.C. Schuster  
127
THE SIGNIFICANCE OF DISSOCIATIVE NUCLEOTIDE CHANGES ACCUMULATION RATE  
IN THE GENOTYPE VARIABILITY OF TICK-BORNE ENCEPHALITIS VIRUS FOR GENE E 
D.O. Kiselev, S.Ju. Bukin, A.I. Paramonov, Ju.P. Dzhioev, V.I. Zlobin
 
128
FUNCTIONAL AND STRUCTURAL CHARACTERISATION OF PPD-B1 PHOTOPERIOD INSENSITIVE ALLELE
 
A.A.
 
Kiseleva, E.A. Salina 
129
PHAGE INFECTION SLOWS DOWN SPECIATION CAUSED BY GENE LOSS AND HORIZONTAL 
GENE TRANSFER OF METABOLIC GENES IN MODELS OF SPATIALLY DISTRIBUTED  
BACTERIAL COMMUNITIES
 
A.I. Klimenko, Yu.G. Matushkin, N.A. Kolchanov, S.A. Lashin 
130
HAPLOID EVOLUTIONARY CONSTRUCTOR 3D: A FRAMEWORK FOR MULTILAYER  
MODELING OF SPATIALLY DISTRIBUTED MICROBIAL COMMUNITIES
 
A.I. Klimenko, Yu.G. Matushkin, Z.S. Mustafin, A.D. Chekantsev, R.K. Zudin, S.A. Lashin 
131
MONOTROPA HYPOPITYS WHOLE GENOME AND TRANSCRIPTOME SEQUENCING DATA
 
E.Z. Kochieva, E.V. Gruzdev, A.V. Beletsky, A.M. Mazur, A.V. Shchennikova, O.V. Shulga,  
M.A. Filyushin, V.V. Kadnikov, A.V. Mardanov, N.V. Ravin, K.G. Skryabin 
132
THE INTERACTION BETWEEN ANAEROBIC RESPIRATORY COMPLEX II  
AND THE FLAGELLAR MOTOR
 
A. Koganitsky, T. Dadosh, V. Kiss, M. Eisenbach
 
133
VIRTUAL BIOLOGY - THE FOUNDATION
 
F.A. Kolpakov
 
134
WHEATDB2: PLANT TRAIT DATABASE AND INFORMATION SYSTEM BASED ON CROP  
ONTOLOGY TERMS
  
E.G. Komyshev, M.A. Genaev, A.V. Akushkina, D.A. Afonnikov
 
135
ASSESSMENT OF TRANSLATIONAL IMPORTANCE OF MAMMALIAN MRNA SEQUENCE  
FEATURES BASED ON RIBO- AND MRNA-SEQ DATA
 
Yu.V. Kondrakhin, R.N. Sharipov, O.A. Volkova 
136
MACROEVOLUTIONARY AND EXPERIMENTAL ASSAYS OF FITNESS LANDSCAPES
 
F. Kondrashov 
137
IT ANALYSIS OF CORNEA ENDOTHELIUM TRANSPORT ABILITY IN CORNEAL TRANSPLANTS 
AFTER HYPOTHERMIC CONSERVATION
  
A.A. Konev, I.G. Palchikova, I.A. Iskakov, L.E. Katkova, G.S. Baturina, E.I. Solenov 
138
INVASIVE ENTOMO-MYCOLOGICAL ASSOCIATION OF P. PROXIMYS AND ITS  
PHYTOPATOGENIC SYMBIONT IN SIBERIA AND EUROPEAN PART OF RUSSIA
 
A. Kononov, A. Blinov, N. Pashenova, N. Percova, Y. Baranchikov
 
139
GENETIC DIVERSITY AMONG EIGHT DENDROLIMUS SPECIES IN EURASIA (LEPIDOPTERA: 
LASIOCAMPIDAE) INFERRED FROM MITOCHONDRIAL COI AND COII, AND NUCLEAR ITS2 MARKERS
 
A. Kononov, K. Ustyantsev,
 
B. Wang, V. Mastro, V. Fet, A. Blinov, Y. Baranchikov  
140
VRN1 GENES VARIABILITY IN TETRAPLOID WHEAT SPECIES WITH A SPRING GROWTH HABIT 
 
I. Konopatskaia, V. Vavilova, E.Ya. Kondratenko, A. Blinov, N.P. Goncharov  
141
GENOME OF BLACK GARDEN ANT: DEFENSE AGAINST VIRUS INVASION?
 
E.A. Konorov, V.A. Scobeyeva, M.A. Nikitin, S.N. Lysenkov, S. Nuzhdin 
142
MOLECULAR EVOLUTION ANALYSIS OF GENES RELATED TO PLANT ROOT HAIR  
AND TRICHOME DEVELOPMENT 
 
D.K. Konstantinov
,
, A.V. Doroshkov
 
143

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
TWO CONGENIC STRAINS PROVE EFFECTS ON CATARACT AND RETINOPATHY BUT  
NOT ON BRAIN NEURODEGENERATION IN SENESCENCE-ACCELERATED OXYS RATS
 
E.E. Korbolina, A.O. Vitovtov, N.G. Kolosova  
144
ASSOCIATION OF MATRIX METALLOPROTEINASES GENE POLYMORPHISM WITH  
THE RISK OF DEVELOPING EXTRA-ARTICULAR SYMPTOMS OF RHEUMATOID ARTHRITIS
M.A. Korolev, Y.B. Ubshaeva, E.A. Letyagina, A.V. Shevchenko, V.F. Prokof’yev, V.I. Konenkov 
145
GENERALISING BETTER: APPLYING DEEP-LEARNING  
TO INTEGRATE DELETERIOUSNESS PREDICTION SCORES FOR WHOLE-EXOME SNV STUDIE
S 
I.O. Korvigo, A.A. Afanasyev
 
146
KU ANTIGEN DISPLAYS THE AP LYASE ACTIVITY ON A CERTAIN TYPE OF DUPLEX DNA 
 
A.A. Kosova, S.N. Khodyreva, O.I. Lavrik  
147
INVOLVEMENT OF VARIOUS CELL DEATH MODALITIES IN CYTOTOXIC ACTIVITY  
OF LACTAPTIN ANALOG
 
O.A. Koval, G.V. Kochneva, A.V. Tkachenko, O.S. Troitskaya, G.F. Sivolobova, E.V. Kuligina,  
A.Y. Yunusova, V.A. Richter
 
148
INCONGRUENT NUCLEAR AND MITOCHONDRIAL GENETIC STRUCTURE IN BAIKALIAN 
AMPHIPODS GMELINOIDES FASCIATUS
 
M.V. Kovalenkova, Zh.V. Petunina, D.Yu. Sherbakov  
149
MATHEMATICAL MODELING A RECIPROCAL INTERACTIONS BETWEEN AUXIN AND ITS PIN 
TRANSPORTERS IN THE ROOT TIP OF A. THALINA L
 
V.V. Kovriznykh, F.V. Kazantsev, N.A. Omelyanchuk, V.V. Mironova
 
150
TWO MODELS OF THE DROSOPHILA GAP GENE NETWORK WITH VARIATION  
OF MATHERNAL INPUT
 
K.N. Kozlov, A.V. Svichkarev, V.V. Gursky, I.V. Kulakovskiy, S.Y. Surkova, M.G. Samsonova
 
151
COMPARATIVE GENOMICS AND TRANSCRIPTOMICS OF CHIRONOMIDAE MIDGES UNDER  
EXTREME CONDITIONS
 
O.S. Kozlova, A.V. Cherkasov, R.M. Devyatiarov, M.D. Logacheva, R. Cornette, T. Kikawada,  
A.A. Przhiboro, O.A. Gusev  
152
COMPARATIVE TRANSCRIPTOMICS PROVIDES NEW INSIGHTS INTO ORIGIN 
OF EXTRAORDINARY RESISTANCE TO DESICCATION IN AUSTRALIAN MIDGE PARABORNIELLA 
TONNOIRI (CHIRONOMIDAE)
 
O.S. Kozlova, E.I. Shagimardanova, L.Kh. Shigapova, R.M. Devyatiarov, M.D. Logacheva,  
R. Cornette, T. Kikawada, O.A. Gusev 
153
TRAJECTORIES OF THE DNA KINKS IN THE SEQUENCES CONTAINING CDS REGIONS
 
L.A. Krasnobaeva, L.V. Yakushevich
 
154
INMETHYL: A TOOL FOR DESIGN OF SPECIFIC PRIMERS FOR METHYLATION PROFILING 
OF COMPLETE CPG ISLANDS
 
G.S. Krasnov, A.V. Kudryavtseva, N.V. Melnikova, A.A. Dmitriev 
155
RTRANS: ANALYSIS OF RNA-SEQ DIFFERENTIAL EXPRESSION USING GLM APPROACH 
AND UNCOVERING ITS BIOLOGICAL BACKGROUND
 
G.S. Krasnov, A.V. Snezhkina, N.V. Melnikova, A.A. Dmitriev,
  
A.V. Kudryavtseva 
156
DIFFERENTIAL EXPRESSION OF ALTERNATIVELY SPLICED TRANSCRIPTS RELATED T 
O ENERGY METABOLISM IN COLORECTAL CANCER
 
G.S. Krasnov, A.V. Snezhkina, I.Y. Karpova, O.L. Kardymon, M.S. Fedorova, A.A. Moskalev,  
A.F. Sadritdinova, K.M. Nyushko, N.V. Melnikova, D.V. Kalinin, A.A. Belova, M.A. Chernichenko, 
K.M. Klimina, D.V. Sidorov, A.Y. Popov, A.A. Dmitriev, A.V. Kudryavtseva
 
157
FAIRDOM: DATA AND MODEL MANAGEMENT FOR SYSTEMS BIOLOGY PROJECTS
  
O. Krebs, R. Kuzyakiv, M. Golebiewski, S. Owen, Q. Nguyen, N. Stanford, K. Wolstencroft,  
J.L. Snoep, B. Rinn, W. Mueller, C. Goble
 
158

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
THE MITOCHONDRIA-TARGETED PLASTOQUINONE SKQ1 AFFECTS DROSOPHILA  
MELANOGASTER LIFESPAN IN VARIOUS ENVIRONMENTS
 
A.V. Krementsova, N.V. Roshina, E.A. Tsybul’ko, O.Y. Rybina, A.V. Symonenko, E.G. Pasyukova
 
159
REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL  
PROCESSING OF GENOMIC URACIL 
 
H.E. Krokan, H.S. Pettersen, R. Mjelle, S.A. Hegre, P. Sætrom, F. Drabløs, A. Sarno,  
A. Galashevskaya, P.A. Aas, N.B. Liabakk, B. Doseth, G. Slupphaug, B. Kavli 
160
EFFECT OF LENTIVIRUS-MEDIATED SHRNA INACTIVATION OF HK1, HK2, AND HK3 GENES  
N COLORECTAL CANCER AND MELANOMA CELLS
 
A.V. Kudryavtseva, M.S. Fedorova, O.L. Kardymon, A.A. Dmitriev, A.I. Afremova, 
D.V. Kochetkov, A.V. Lipatova, A.F. Sadritdinova, I.Y. Karpova, K.M. Nyushko, D.V. Kalinin, 
N.N. Volchenko, N.V. Melnikova, A.A. Belova, M.A. Chernichenko, K.M. Klimina, N.V. Nasedkina, 
A.S. Zasedatelev, D.V. Sidorov, A.Y. Popov, G.S. Krasnov, A.V. Snezhkina  
161
COMPUTER SOFTWARE FOR STATISTICAL ANALYSIS OF GENES LOCATION RELATIVE  
TO CHROMOSOME CONTACTS REVEALED BY CHIA-PET
 
E.V. Kulakova, A.M. Spitsina  
162
SYSTEMIC ROLE OF ALLELIC VARIANTS IN A 2Q22 REGION IN MAJOR AGE-RELATED  
DISEASES AND LIFESPAN
 
A.M. Kulminski, L. He, I. Culminskaya, Y. Loika, Y. Kernogitski, K.G. Arbeev, E. Loiko,  
L. Arbeeva, O. Bagley, M. Duan, A. Yashkin, F. Fang, M. Kovtun, S.V. Ukraintseva, D. Wu,  
A.I. Yashin 
163
COMPARATIVE EXPRESSION LANDSCAPES IN REPLICATIVE AND STRESS INDUCED  
PREMATURE SENESCENCE
 
K.C. Kural, N. Tandon, O.V. Kel-Margoulis, A. Baranova
 
164
TRANSCRIPTOMICS OF THE CRYOBIOTIC LEECH OZOBRANCHUS JANTSEANUS 
S.V. Kuznecova, D. Suzuki, M.D. Logacheva, O.S. Kozlova, T. Kikawada, R.M. Sabirov, O.A. Gusev
 
165
A MATHEMATICAL MODEL FOR PREDICTING OF IGD–CD27+B LYMPHOCYTES LEVELS  
IN DONORS’ BLOOD
 
S.R. Kuznetsov, I.V. Kudryavtsev, A.V. Orekhov, A.V. Polevshchikov, M.K. Serebriakova,  
V.I. Shishkin
 
166
TARGET ENRICHMENT TECHNOLOGIES FOR APPLIED RESEARCH
 
D.A. Kwon 
167
CHARACTERIZATION OF NOVEL ALKANE-DEGRADING AND BIOSURFACTANT-PRODUCING 
STRAIN TSUKAMURELLA TYROSINOSOLVENS PS2
A.V. Laikov, E.A. Boulygina, V.A. Romanova, T.V. Grigorieva
 
168
3D MAP OF PROLIFERATION ACTIVITY IN ARABIDOPSIS THALIANA ROOT TIPS: TRANSITION 
DOMAIN BOUNDARIES AND ITS BILATERAL SYMMETRY 
V.V. Lavrekha, T. Pasternak, N.A. Omelyanchuk, V.B. Ivanov, V.V. Mironova  
169
POLY(ADP-RIBOSE) POLYMERASE 1 AND REGULATION OF DNA REPAIR
 
O.I. Lavrik
 
170
TOWARDS UNDERSTANDING THE DYNAMICS OF DEATH RECEPTOR NETWORKS
  
O.I. Lavrik 
171
DOES THYROID DIVERGENCE SERVE AS A DRIVER OF SPECIATION IN CYPRINID FISHES  
OF THE GENUS BALLERUS (TELEOSTEI)
? 
B.A. Levin, A.A. Bolotovskiy, M.A. Levina, A.V. Nedoluzhko, K.G. Skryabin, S.M. Rastorguev,  
E.B. Prokhortchouk
 
172
DIFFERENTIAL ANALYSIS OF THREE-DIMENSIONAL (3D) GENOMICS DATA
 
G. Li 
173

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
GENOTYPE DISTRIBUTION IN PATIENTS WITH CHRONIC HEPATITIS C ANALYSIS USING  
MULTIFACTOR DIMENSIONALITY REDUCTION METHOD
 
A.D. Liaudanski, M.S. Rodzkin, V.S. Pankratov, D.E. Danilau, I.A. Karpov, O.G. Davydenko
 
174
POSTGENOME MEDICINE AS N-OF-ONE SCIENCE
  
A.V. Lisitsa, E.V. Kolker, H. Chen, V.E. Frankevich 
175
DNA DUPLEX STRUCTURE AND THERMODYNAMICS BY MOLECULAR DYNAMICS SIMULATION
 
A.A. Lomzov, D.V. Pyshnyi 
176
EVOLUTION OF PHENOTYPIC CONTROL BY NEW GENES THROUGH INTEGRATING  
AND REWIRING OF ANCESTRAL EXPRESSION NETWORKS
 
M. Long 
177
TARGETED SPATIAL GENOME MODIFICATION IN TOPOLO-GICALLY ASSOCIATING DOMAINS 
STRUCTURE IN MOUSE EMBRYONIC STEM CELLS
 
V.A. Lukyanchikova, N.R. Battulin, O.L. Serov  
178
THE DENSITY OF WOLBACHIA STRAIN WMELPOP IN DROSOPHILA MELANOGASTER BRAIN  
IS INVERSELY RELATED TO THE LEVEL OF HSP67BC GENE EXPRESSION
 
D.A. Malkeyeva, E.V. Kiseleva
 
179
PREDICTION OF FUNCTIONAL EFFECTS OF REGULATORY SEQUENCE VARIATIONS
 
M. Malkowska, J. Zubek, D. Plewczynski, L.S. Wyrwicz  
180
MOLECULAR EVOLUTION AND SYSTEMATICS OF FLAT LEECHES (HIRUDINEA: GLOSSIPHONIIDAE)
 
N.B. Mandzyak, I.A. Kaygorodova
 
181
PREDICTION OF STRUCTURAL PROPERTIES OF UNCHARACTERIZED PROTEINS FROM 
THEIR POST-CLEAVAGE MASS SPECTRA BY A MULTIVARIATE STATISTICAL MODEL 
 
O.A. Markelov, A.R. Kayumov, M.I. Bogachev
 
182
ON THE POSSIBLE IMPACT OF EXOGENOUS 8-OXO-2’-DEOXYGUANOSINE ON DNA SYNTHESIS, 
DAMAGE AND REPAIR IN AGING CELL CULTURES AND ORGANISM 
 
N.V. Marmiy, G.V. Morgunova, D.S. Esipov, A.N. Khokhlov
 
183
MOLECULAR EVOLUTION ANALYSIS OF RNA-BINDING NIP7 PROTEIN FROM DEEP-  
AND SHALLOW-WATER ARCHAEA 
K.E. Medvedev, D.A. Afonnikov  
184
HIGH TEMPERATURE AND PRESSURE INFLUENCE ON INTERDOMAIN INTERFACE OF THE NIP7 
PROTEINS FROM P. ABYSSI AND P. FURIOSUS: MD SIMULATION RESEARCH
 
K.E. Medvedev, D.A. Afonnikov  
185
SITEX 2.0: FUNCTIONAL SITES PROJECTION ON ALTERNATIVE SPLICED ISOFORMS  
AND HOMOLOGOUS GENES 
 
I.V. Medvedeva, P.S. Demenkov, V.A. Ivanisenko  
186
PROGRAM COMPLEX ICGENOMICS FOR ANALYSIS OF HIGH-THROUGHPUT SEQUENCING 
EXPERIMENTS
 
I.V. Medvedeva, A.O. Bragin, K.V. Gunbin, P.S. Demenkov, O.V. Vishnevsky, A.M. Spitsina,  
F.M. Naumenko, V.N. Babenko, N.L. Podkolodnyy, Y.L. Orlov 
187
NONTHERMAL IMPACT TERAHERTZ RADIATION ON THE LIVING SYSTEMS
 
I.A. Mescheryakova, E.V. Demidova, T.N. Goryachkovskaya, E.A. Demidov, A.V. Bryanskaya,  
S.V. Sergeeva, S.L. Kiselev, M.A. Lagarkova, G.N. Kulipanov, A.I. Semenov, N.A. Vinokurov,  
N.A. Kolchanov, V.M. Popik, S.E. Peltek 
188
BIOMARKERS OF AGE IN THE “STATIONARY PHASE AGING” MODEL 
G.V. Morgunova, D.S. Esipov, M.V. Marmiy, A.N. Khokhlov 
189
K-MER FREQUENCY DISTRIBUTION OF EUKARYOTIC PROTEOMES 
A.A. Morozov 
190

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
CAN LONG ANTIPARALLEL OPEN READING FRAMES BE ENCODING ESSENTIAL GENES 
IN PROKARYOTIC GENOMES?
 
D.M. Moshensky, A.V. Alexeevski  
191
GEROPROTECTOR AND CRITERIA FOR ITS EVALUATION
 
A. Moskalev, M. Shaposhnikov, E. Proshkina, V. Tsvetkov, A. Fedintsev, E. Chernyagina,  
A.
 
Zhavironkov
 
192
PHOSPHORYLATION OF ΑB-CRYSTALLIN: EFFECTS OF AGING AND CARDIOMYOPATHY 
 
N.A. Muraleva, V.A. Devyatkin, N.A. Kolosova
 
193
ADVANCED CAPABILITIES OF VISUALIZATION AND ANALYSIS OF CULTURAL MODELS
 
E.R. Muslikhov, L.A. Strukova  
194
ORTHOSCAPE: A CYTOSCAPE PLUGIN FOR EVOLUTIONARY ANALYSIS OF GENE NETWORKS
 
Z.S. Mustafin, D.A. Afonnikov, K.V. Gunbin, Yu.G. Matushkin, S.A. Lashin
 
195
CROSSING VALLEYS AND REACHING PEAK ON THE FITNESS LANDSCAPES IN MICROBIAL 
COMMUNITIES UNDER VARIOUS ECOLOGICAL CONDITIONS: A SIMULATION STUDY
 
Z.S. Mustafin, D.A. Afonnikov, Yu.G. Matushkin, S.A. Lashin
 
196
POLYMORPHISM OF THE VRN-A1 EXON-4 AND EXON-7 IN POLYPLOID WHEAT
 
A.F. Muterko, E.A.
 
Salina 
197
PROTEOMIC OF TCA - EXTRACTED COMPOUNDS, ISOLATЕD FROM HUMAN BLOOD 
SERUM REVEALED NEW POTENTIAL BIOMARKERS, ASSOSIATED WITH AUTOIMMUNE 
AND HEMATOONCOLOGICAL DISEASES
 
S. Myronovkij, M. Starykovych, Y. Bobak, N. Negrych, T. Nehrych, M. Shorobura, O. Shalay, 
S. Souchelnytskyi, R. Stoika, Y. Kit   
 
 
 
 
 
     198
COMPUTER AIDED DRUG DESIGN: DEVELOPMENT MODELS FOR SPECIFICITY, 
POLYPHARMOCOLOGY AND MEMBRANE PERMEABILITY
 
G.N. Sastry, S. Janardhan, A.S. Gaur, V. Poroikov
 
199
STUDY ON THE REGULATION OF CELL DIVISION DURING EARLY FRUIT DEVELOPMENT IN TOMATO
  
H. Nariyama, T. Shibuya, Y. Kanayama  
2008
WHOLE GENOME OF THE WOOLY MAMMOTH: EVOLUTION THROUGH MILLENIA
 
A.V. Nedoluzhko, A.S. Sokolov, F.S. Sharko, E.S. Boulygina, S.V. Tsygankova, A.N. Tikhonov,  
K.G. Skryabin, E.B. Prokhortchouk
 
201
REGULATION OF THIOREDOXIN GENES EXPRESSION IN DESICCATION-TOLERANT 
INSECT POLYPEDILUM VANDERPLANKI
 
A.A. Nesmelov, E.I. Shagimardanova, M.D. Logacheva, R. Cornette, T. Kikawada, O.A. Gusev
 
202
DEVELOPMENT OF MICROSATELLITE MARKERS ACCORDING TO BAC SEQUENCING  
DATA AND THEIR PHYSICAL MAPPING TO THE BREAD WHEAT 5B CHROMOSOME
 
M.A. Nesterov, D.A. Afonnikov, E.M. Sergeeva, L.A. Miroshnichenko, M.K. Bragina,   
A.O. Bragin, G.V. Vasiliev, E.A. Salina
 
203
CMSEARCH: TOOL FOR SEARCHING TFBS COMPOSITE MODULES IN DNA SEQUENCES
 
S.I. Nikitin, E.S. Cheryomushkin  
204
A CONGESTION GAME MODEL FOR VIRTUAL DRUG SCREENING IN A DESKTOP GRID
 
N.N. Nikitina, E.E. Ivashko 
205
MECHANICS OF PLANT CELL UNIDIRECTIONAL GROWTH
 
S.V. Nikolaev, S.K. Golushko, U.S. Zubairova, D.A. Afonnikov  
206
IN SILICO SCREENING FOR SULFONATE-BASED INHIBITORS AGAINST PROMISING 
ANTICANCER TARGETS
 
D.K. Nilov, I.V. Gushchina, V.K. Švedas  
207

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
PROTEOMIC SCREENING FOR AMYLOID-FORMING PROTEINS IN BACTERIA ESCHERICHIA COLI
 
A.A. Nizhnikov, K.S. Antonets, K.V. Volkov, A.L. Maltseva, A.P. Galkin
 
208
IDENTIFICATION OF STURGEON SPECIES WITH MTDNA AND MICROSATELLITE MARKERS  
IN BELARUS 
 
A.Yu. Nosova 
209
MEMBRANE-ASSOCIATED KINASE REGULATORS OF MAKR FAMILY GENES IN ARABIDOPSIS 
THALIANA L.
 
D.D. Novikova, N.A. Omelyanchuk, V.V. Mironova  
210
MAPPING THE INTERACTION SITE FOR THE MESOBUTHUS SCORPION TOXINS IN THE VOLTAGE-
GATED POTASSIUM CHANNEL KV1.2 
 
V.N. Novoseletsky, A.D. Volyntceva, K.V. Shaitan 
211
DISTRIBUTION OF 2541-2542DELCA KDPD FRAMESHIFT MUTATION IN GENOMES  
OF MYCOBACTERIUM TUBERCULOSIS FROM IRKUTSK OBLAST AND YAKUTIA
 
O. Ogarkov, V. Sinkov, I. Mokrousov, S. Zhdanova, P. Khromova, E. Orlova
 
212
VASCULAR ENDOTHELIAL GROWTH FACTOR POLYMORPHISMS ARE ASSOCIATED 
WITH THE EARLIER ONSET OF RHEUMATOID ARTHRITIS
 
V.O. Omelchenko, M.A. Korolev, E.A. Letyagina, A.V. Shevchenko, V.F. Prokof’yev,  
T.I. Pospelova, V.I. Konenkov
 
213
THEORETICAL MODEL OF MITOTIC SPINDLE MICROTUBULE GROWTH FOR FRAP CURVE 
INTERPRETATION
 
L.V. Omelyanchuk, A.F. Munzarova, T.Y. Mikhailova
 
214
SEQUENCING OF CONIFER GENOMES USING NGS
 
N.V. Oreshkova, Yu.A. Putintseva, D.A. Kuzmin, V.V. Sharov, V.V. Biryukov, S.V. Makolov,  
K.V. Krutovsky
 
215
CLUSTER ANALYSIS OF STRESS-INDUCED DUPLEX DESTABILIZATION (SIDD) 
PROFILES FOR E. COLI PROMOTERS
 
M.A. Orlov, A.A. Ryasik, E.A. Temlyakova, A.A. Sorokin 
216
COMPUTER ANALYIS OF DISTAL GENE REGULATION USING CHROMOSOME CONTACTS DATA
 
Y.L. Orlov, E.V. Kulakova, A.G. Bogomolov, V.N. Babenko, G. Li 
217
DIOXIN-MEDIATED UPREGULATION OF ONCOSTATIN M IN U937 MACROPHAGES
 
D.Y. Oshchepkov, E.V. Kashina, V.A. Mordvinov, D.P. Furman 
218
IN SILICO MOUSE CHROMOCENTERS CONTENT
 
D.I. Ostromyshenskii, A.S. Komissarov, I.S. Kuznetsova, O.I. Podgornaya 
219
THE GENOME WIDE ANALYSIS OF THE LARGE TANDEM REPEATS IN THE CLOSELY RELATED GENOMES
 
D.I. Ostromyshenskii, O.I. Podgornaya 
220
ELECTROSTATICS: A NEW OLD GENOME SELECTION FACTOR
 
A.A. Osypov 
221
DIFFERENTIAL EXPRESSION IN HELIX LUCORUM STATOCYSTS UNDER MICROGRAVITY  
CONDITIONS
 
A.A. Osypov, P. Kolosov, N. Aceyev, E. Chesnokova, M. Roshchin, N. Bal, P. Balaban
 
222
TOWARDS A NEUROBIOLOGICALLY REASONABLE C. ELEGANS NERVOUS SYSTEM SIMULATION: 
NEURON, MUSCLE AND SIGNAL PROPAGATION MODELLING
 
A.Yu. Palyanov, Kh.V. Samoilova
  
223
SEARCH FOR FUNCTIONAL NF-KB BINDING SITES VIA META-ANALYSIS OF NGS EXPERIMENTS 
IN HUMAN CELL LINES
N. Panyushev, E. Lomert, D. Tentler, A. Predeus
 
224

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THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
NEW INSIGHTS INTO THE REGULATION OF REACTIVE OXYGEN SPECIES BY AUXIN THROUGH 
GENE EXPRESSION ANALYSIS
I.A. Paponov, V. Budnyk, T. Khodus, M. Paponov, K. Palme
 
225
IDENTIFICATION OF RECOMBINATION SITES IN THE GENOMES OF THE EUROPEAN SUBTYPE  
OF TICK BORNE ENCEPHALITIS VIRUS
A.I. Paramonov, Yu.P. Dzhioev, I.V. Kozlova
 
226
DARWINIAN GENETIC DRIFT
D.V. Parkhomchuk, A.C. McHardy 
227
IMPACT OF 105-DAY ISOLATION CONDITIONS ON PROTEINS EXPRESSED IN ENDOTHELIAL 
CELLS, IN THE FRAMEWORK OF THE “MARS-500” PROJECT
L.Kh. Pastushkova, D.N. Kashirina, A.S. Kononikhin, A.G. Brzhozovsky, I.V. Dobrokhotov,  
E.S. Tiys, V.A. Ivanisenko, E.N. Nikolaev, I.M. Larina
 
228
THE ROLE OF KINETOCHORE-DRIVEN MICROTUBULE FORMATION IN DROSOPHILA SPINDLE 
ASSEMBLY
G. Pavlova, J. Popova, A. Munzarova, J. Galimova, A. Razuvaeva, F. Renda, P. Somma,  
A. Pindyurin, M. Gatti
 
229
MICROBIAL COMMUNITY OF THE OIL SITE OF THE UZON CALDERA (KAMCHATKA)
S.E. Peltek, A.V. Bryanskaya, Y.E. Uvarova, A.S. Rozanov, T.V. Ivanisenko, T.K. Malup,  
V.A. Ivanisenko, E.V. Lazareva, O.V. Saik, S.M. Zhmodik, O.P. Taran, N.M. Slynko, 
S.V. Shekhovtsov, V.N. Parmon, N.L. Dobretsov, N.A. Kolchanov  
230
PQ: A NEW PROGRAM FOR PHYLOGENETIC RECONSTRUCTION
D. Penzar, M.S. Krivozubov, S.A. Spirin  
231
THE BIOINFORNATIONAL COMPARISON OF CRISPR/CAS SYSTEM STRUCTURE OF YERSINIA 
PSEUDOTUBERCULOSIS STRAINS ISOLATED FROM DIFFERENT REGIONS
N.P. Peretolchina, Y.P. Dzhioev
 
, A.Y. Borisenko, E.A. Voskresenskaya, A.I. Paramonov,
  
L.A. Stepanenko, V.I. Zlobin 
232
SEARCH OF GENETIC SEQUENCES OF POTATOES IN DATABASES
A.I. Perfileva 
233
HEAT SHOCK PROTEINS OF POTATO IN VITRO UNDER HEAT AND BIOTIC STRESS
 
A.I. Perfileva, E.G. Rikhvanov 
234
MOSAIC GENE NETWORK MODELLING IDENTIFIED NEW REGULATORY MECHANISMS IN HCV 
INFECTION
 
O.V. Petroskaya, E.D. Petrovskiy, E.L. Mishchenko, I.N. Lavrik, V.A. Ivanisenko
 
235
GUT MICROBIOTA IN CASE OF PARKINSON'S DISEASE AND OTHER NEUROLOGICAL 
PATHOLOGIES: COMPARATIVE STUDY 
V.A. Petrov, V.M. Alifirova, I.V. Saltykova, Y.B. Dorofeyeva, A.V. Tyakht, E.S. Kostryukova,  
A.E. Sazonov
 
236
WORKFLOW FOR EXOME SEQUENCING IN IDENTIFICATION OF DE NOVO MUTATION  
IN THE NCL6 GENE
 
D.A. Petukhova, N.R. Maksimova, P.I. Guryeva, V.S. Kaymonov, M.T. Savvina 
237
MIRNA BINDING SITES IN THE MRNA OF HUMAN TITIN GENE
 
I.V. Pinsky, A.T. Ivashchenko, S.B. Labeit
 
238
BIOSTORE: A CLOUD-COMPATIBLE HUB FOR BIOINFORMATICS RELATED TOOLS AND PLATFORMS
 
S. Pintus, T. Valeev, I. Yevshin, F. Kolpakov
 
239
COMPUTATIONAL MODEL FOR MAMMALIAN CIRCADIAN OSCILLATOR INTERACTING  
WITH NAD+ / SIRT1 PATHWAY
 
O.A. Podkolodnaya, N.N. Tverdokhleb, N.L. Podkolodnyy
 
240

18
THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
COMPUTER ANALYSIS OF BIOLOGICAL NETWORKS OF MAMMALIAN CIRCADIAN OSCILLATOR
 
N.L. Podkolodnyy, N.N. Tverdokhleb, E.O. Sambilova, S.A. Lobynya, Z.D. Yakubova,  
O.A. Podkolodnaya
 
241
QUANTITATIVE CONTRIBUTION OF IL2RΓ TO THE DYNAMIC FORMATION OF IL2-IL2R COMPLEXES
 
L.F. Ponce, K.García-Martínez, K. León 
242
EPIGENOMIC CHANGES IN POSTMORTEM BRAINS OF HUMAN ALCOHOLICS
 
I. Ponomarev 
243
PUNCTUATED EVOLUTION: THE RELATIONSHIP BETWEEN RARE MUTATIONS  
AND CLADOGENESIS OF VERTEBRATES
 
K. Popadin, K. Gunbin 
244
TASSE: A NEW APPROACH TO SOLVENT TREATMENT IN MOLECULAR DYNAMICS
 
A.V. Popov, Yu.N. Vorobjev, D.O. Zharkov 
245
COMPUTER-AIDED DRUG REPURPOSING: NEW USES FOR OLD DRUGS OR FILLING GAPS  
IN BIOMEDICAL KNOWLEDGE?
 
V.V. Poroikov, D.A. Filimonov, A.A. Lagunin, T.A. Gloriozova 
246
INTRON EVOLUTION: SLIDING AND VARIABILITY OF LENGTH
 
I.V. Poverennaya, D.D. Gorev, T.V. Astakhova, M.A. Roytberg  
247
DNA DAMAGE AND GENERATION OF REACTIVE OXYGEN SPECIES BY PLATINUM DRUGS: 
EXPERIMENTS ON BACTERIA
 
E.V. Prazdnova, V.A. Chistyakov, M.S. Mazanko, M.N. Churilov, V.K. Chmyhalo  
248
GENEQUERY: GLOBALLY CONNECTED NETWORKS OF GEO TRANSCRIPTIONAL 
PROFILES SHOW HYPOTHESIS GENERATION POTENTIAL AND REVEAL THAT 
TOCOPHEROLS RESCUE TREM2-ASSOCIATED MICROGLIAL DYSFUNCTION
 
A.V. Predeus, T. Ulland, Y. Wang, V. Lampropoulou, W. Song, I. Arbuzov, F. Towfic, S. Gilfilan,  
E. Loginicheva, B.T. Edelson, B. Zeskind, M. Colonna, M.N. Artyomov
 
249
THE ROLE OF HUNTINGTIN PROTEIN-PROTEIN INTERACTIONS IN THE PROCESSES 
OF CHANGING AND MAINTENANCE OF NEUROTRANSMISSION IN HIPPOCAMPUS
 
A.L. Proskura, S.O. Vechkapova, T.A. Zapara, A.S. Ratushniak 
250
STUDY OF ARMILLARIA BOREALIS PATHOGENICITY BY THE COMPARATIVE WHOLE GENOME 
SEQUENCING 
Yu.A. Putintseva, I.N. Pavlov, N.V. Oreshkova, V.V. Sharov, D.A. Kuzmin, S.V. Makolov,  
K.V. Krutovsky
 
251
RNA SEQ ANALYSIS OF MARINE AND FRESHWATER FORMS OF THREE-SPINED STICKLEBACK 
(GASTEROSTEUS ACULEATUS). EVOLUTIONARY AND PHYSIOLOGICAL MECHANISMS  
OF ADAPTATION 
S.M. Rastorguev, A.V. Nedoluzhko, A.M. Mazur, E.B. Prockhorchouk
 
252
GENETIC AND MOLECULAR MECHANISMS CRUCIAL FOR HYPERTENSION DEVELOPMENT I 
N THE ISIAH RATS
 
O.E.
 
Redina, L.O.
 
Klimov, M.A. Ryazanova, L.A. Fedoseeva, T.O. Abramova, Yu.V. Alexandrovich,  
S.E. Smolenskaya, Ye.V. Antonov, N.I. Ershov, V.M. Efimov, A.L. Markel
 
253
ROLE OF MEMBRANE POTENTIAL IN NITRITE UTILIZATION BY ESCHERICHIA COLI CELLS UNDER 
LOW SUBSTRATE CONCENTRATIONS: THE MATHEMATICAL MODEL 
 
N.A. Ree, V.A. Likhoshvai, T.M. Khlebodarova  
254
MODELING RESTRICTION-MODIFICATION SYSTEMS: EXPRESSING TOXIC MOLECULES  
WITHIN A CELL 
A. Rodic, M. Djordjevic
 
255
GENETIC FITNESS OF DEAF PEOPLE IN THE SAKHA REPUBLIC
  
G.P. Romanov
 
, N.A. Barashkov
 
, F.M. Teryutin, L.A. Klarov, A.V. Solovyev, N.N. Gotovtsev,  

19
THE TENTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE\SYSTEMS BIOLOGY
V.G. Pshennikova, N.N. Sazonov, I.V. Morozov, A.A. Bondar, L.U. Dzhemileva, 
E.K. Khusnutdinova, O.L. Posukh, S.A. Fedorova 
256
EVOLUTION OF MITOCHONDRIAL GENOMES IN BAIKALIAN AMPHIPODS 
E.V. Romanova, V.V. Aleoshin, K.V. Mikhailov, R.M. Kamaltynov, M.D. Logacheva,  
E.A. Sirotinina, D.Yu.
 
Sherbakov
 
257
GENETIC DIVERSITY AND METABOLISM OF THE GARGA HOT SPRING MICROBIAL MAT 
 
A.S. Rozanov, A.V. Bryanskaya, T.K. Malup, T.V. Ivanisenko, Yu.E. Uvarova, S.E. Peltek  
258
NEUROTHROPHIN SIGNALING PATHWAY IN DEVELOPMENT OF ALZHEIMER’S DISEASE-LIKE 
PATHOLOGY
 
E.A. Rudnitskaya, N.A. Muraleva, N.A. Stefanova, N.G. Kolosova 
259
DEVELOPMENT OF CATARACT AS THE BASIC SELECTION TRAIT IN THE ONTOGENY  
OF SENESCENCE-ACCELERATED OXYS RATS